Clustering without RAM
Published:
My next research project involves determining groups of genes that derive from a common ancestor (usually called ‘orthologs’). To do this, we often take a bunch of gene sequences, quantify their pairwise similarity in some fashion, and then cluster them into groups of genes that are more similar to each other than to other clusters. I’m oversimplifying a lot here to keep this brief, so keep in mind that the actual calculations of those “pairwise distances” can involve a bunch of stuff.